Chewable Co-Enzyme Q10
Specially Formulated For Enhanced Absorption
Chewable Co-Enzyme Q10 tablets, provided by Westlake Laboratories®, contains pure co-enzyme Q10 (ubiquinone) and not shorter isoprenoid chain lipids such as Q9 or Q8 , which can be found as a large constituent of inferior co-Q enzyme products found on the market today. The Co-Q enzyme formulation in the chewable tablet has a unique lipophilic (fat-soluble) base that promotes the absorption of ubiquinone.
Functions
As an important rate-limiting nutrient in the electron transport chain of the Mitochondria, Co-enzyme Q10 is a cofactor found to be critical in cellular respiration. Oxidative phosphorylation http://en.wikipedia.org/wiki/Oxidative_phosphorylation is biochemical pathway through which energy is created from burning nutrients to form adenosine triphosphate (ATP) “the body’s energy currency”. Co-enzyme Q10 is essential for the health of all human organs because nearly all cellular activities are dependent upon energy derived from ATP.
The recent rise in the general popularity of Co-enzyme Q10 stems from data that demonstrates this naturally occurring antioxidant nutrient retards free radical formation in biological systems as well as from studies that suggest the enzyme is important in protecting heart health.
Structure and Mechanism of Action
Co-enzyme Q10 is a benzoquinone, whose structure resembles vitamin E and vitamin K but with differing properties. http://en.wikipedia.org/wiki/Coenzyme_Q10
Biochemically, it can function much like vitamin E, as Co-Q10 participates in antioxidant and free radical scavenging reactions.
Indications
Healthy humans who consume a well-balanced diet have the ability to synthesize co-enzyme Q10. Unhealthy individuals and those on an inadequate diet may not synthesize co-enzyme Q10 in sufficient quantity. Specially formulated Chewable Co-Enzyme Q10 tablets may be a useful nutritional adjunct for individuals whose co-enzyme Q10 requirements are not adequately met through endogenous biosynthetic means to produce the molecule, or for those individuals who have difficulty with absorption of fatsoluble nutrients.
The NHANES I and II studies demonstrate that many Americans do not have an adequate diet. Rather, their intake of most water soluble vitamns, vitamin A and some minerals and trace elements is insufficient.
Many of these nutrients are essential for the biosynthesis of co-enzyme Q10. Further, statin drugs are know to inhibit enzyme co Q10. In addition, it has been shown that in disease states, nutrients from food sources may not necessarily be absorbed or bioavailable.
According to Folkers and other experts, co-enzyme Q10 should be considered an essential nutrient, as it is well established that co-enzyme Q10 is essential for the health of every cell in the human body.
Formula
Chewable Co-Enzyme Q10 (200 mg)
Each tablet contains:
Co-Enzyme Q10 (ubiquinone)* ... 200 mg
Vitamin E ... 400 I.U.
Suggested Use
Chew one tablet daily as a dietary supplement, or as directed by physician.
Side Effects
No adverse effects have been reported.
References
Bliznakov EG: Coenzyme Q, the immune system and aging. In:
Biochemical and Clinical Aspects of Coenzyme Q10, vol 3, Folkers K
and Yamamura Y, Eds., Elsevier Science Publishers, 1981, pp. 311-326.
Folkers K, Littarru GP, Yamagami Y, Eds., Biochemical and Clinical Aspects of Coenzyme Q, Volume 6. Elsevier Science Publishers, 1991.
Greenberg S, Frishman WH: Coenzyme Q10: a new drug for
cardiovascular disease. J Clin Pharmac 1990;30:596-608.
Guanmieri C et al: The effect of treatment with coenzyme Q10 on the
mitochondrial function and superoxide radical formation in the cardiac
muscle hypertrophied by mild aortic stenosis. J Mol Cell Cardiol
1987;19:63-71.
Kamikawa T, Kobayashi A, et al: Effects of coenzyme Q10 on
exercise tolerance in chronic stable angina pectoris. Am J Cardiol
1985;56:247-251.
Langsjoen Per H et al: Long-term safety and efficacy of coenzyme
Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol
1990;
Ghirlanda, et al., "Evidence of plasma CoQ10-lowering effect of HMG-COA reductase inhibitors: a double-blind, placebo-controlled study," Journal of Clinical Pharmacology. 1993 Mar; 33(3):226-229.
Disclaimer
These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
We at Westlake labs take heavy metal contamination seriously and thus test our products routinely to assure quality. We offer a survey compared to big box store brands randomly obtained over the last year.